NCIS, in its 21st season, has seen several characters leave the show over the years. Zoe McLennan, who played Agent Brody, exited amid behind-the-scenes controversies revealed by former showrunner Jeffrey Lieber. Cote de Pablo’s departure as Ziva David raised questions, with conflicting statements about her reasons. Michael Weatherly’s exit as Tony DiNozzo after 13 seasons was driven by a desire for new challenges. Pauley Perrette, portraying Abby Sciuto for 15 seasons, left amid reports of conflicts with Mark Harmon and his dog’s on-set behavior. Emily Wickersham’s departure as Ellie Bishop in season 18 was amicable, as she pursued a focus on family. Mark Harmon’s recent exit in season 19 marked a career shift, citing the need for freshness and age-related considerations. The show continues to evolve with characters coming and going, maintaining its enduring popularity.